WCX-O Columns

SMT-WCX-O Mixed-Mode silica-based columns contain weak cation exchange with hydrophobic alkyl functional groups which are developed for reversed-phase, weak cation-exchange, and hydrophilic interaction liquid chromatography modes. SMT WCX-O consists of chemically attached hydrophobic alkyl chain with carboxylic acid for hydrophobic reversed-phase and weak cation-exchange functionality. The technique of SAM is used in the bonding process to significantly increase the functional ligand density.

Special features of SMT WCX-O Mixed-Mode columns include:

  • Compatible with reversed-phase, weak cation-exchange, and hydrophilic interaction liquid chromatography modes
  • Superior selectivity and efficiency in the separation of proteins and biomolecules

Are you looking for a column with custom specifications (pore size, particle size, length and/or I.D.) not available on this site? Please contact us as we can manufacture the exact column you need.

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  • SMT SAM WCX-O – Mixed-Mode WCX-O Column

    WCX-O columns for separation of basic and neutral compounds. These USP L85 columns contain weak cation exchange with hydrophobic alkyl functional groups which are developed for reversed-phase, weak cation-exchange, and HILIC modes.

    WCX-O columns for separation of basic and neutral compounds. These USP L85 columns contain weak cation exchange with hydrophobic alkyl functional groups which are developed for reversed-phase, weak cation-exchange, and HILIC modes.

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  • SMT SAM WCX-O – Guard Column

    WCX-O Guard columns are expendable small columns designed to remove anything that may interfere with the separation or shorten the lifetime of the primary column.

    WCX-O Guard columns are expendable small columns designed to remove anything that may interfere with the separation or shorten the lifetime of the primary column.

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