Diol Columns

SMT Diol column is developed as an alternative for silica column used in normal phase separation methods. The Diol [-OH] functional group is controlled, and as such, provides more reproducible separation when compared to separation on silanols [-OH] from bare silica surface. Furthermore, the hydrogen bonding on the OH functional group on Diol packing material is not as strong as that of bare silica. This results in a reduced interaction of polar compounds on the column. SMT-Diol can be used in normal and reversed-phase separation of pesticides, herbicides, pharmaceutical metabolites, polar natural products, proteins, peptides and other polar biomolecules.

Unique features:

  • High loading capability and improved sample recovery
  • High reproducibility of bonded ligand resulting in consistent separation
  • Increased longevity provided through “Total Coverage”

Two types of SMT Diol are available:

  • Diol1: Consists of acid-catalyzed cleavage of 3-(2,3-epoxypropoxy) propyl as the functional ligand
  • Diol2: Consists of acid-catalyzed cleavage of 5,6-epoxyhexyl as the functional ligand

Just like the silica substrate, both of Diol1 and Diol2 can be subjected to further treatment or modification with another functional ligand for special applications.

Are you looking for a column with custom specifications (pore size, particle size, length and/or I.D.) not available on this site? Please contact us as we can manufacture the exact column you need.

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  • SMT SAM Diol – Normal Phase Diol Column

    Diol columns for separation of pesticides, herbicides, pharmaceutical metabolites, polar natural products, proteins, peptides and other polar biomolecules. The Diol functional group is controlled, and provides more reproducible separation compared to on bare silica.

    Diol columns for separation of pesticides, herbicides, pharmaceutical metabolites, polar natural products, proteins, peptides and other polar biomolecules. The Diol functional group is controlled, and provides more reproducible separation compared to on bare silica.

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  • SMT SAM Diol – Guard Column

    Diol Guard columns are expendable small columns designed to remove anything that may interfere with the separation or shorten the lifetime of the primary column.

    Diol Guard columns are expendable small columns designed to remove anything that may interfere with the separation or shorten the lifetime of the primary column.

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