C4: MEB4 Columns

SMT manufactures columns with short carbon chains for rapid analysis of basic, neutral, and mildly acidic drugs and small molecules.  These columns provide excellent baseline resolution for small basic molecules including therapeutic drugs.  The bonding scheme ensures proper deactivation substrate silanols and resistance to acid hydrolysis.
 
MEB (Methyl, Ethyl, and Butyl) columns are particularly superior to other reversed-phases in the separation of compounds that show very strong hydrophobic interaction with hydrophobic stationary phases such as C18 and C8.  MEB columns offers extremely fast mass transfer and high efficiency in the separation of these compounds.  Specific applications include separation of proteins, peptides and food additives.  
 
SMT offers 3 different MEB phases of varying carbon loads for optimal selectivity
 
MEB1 series:  SMT MEB column with the shortest carbon length. The functional ligand is methyl, C1 with carbon analysis results of about 1% carbon load.  In these series, a very high density of the functional ligand, methyl molecule or C1, is achieved through a novel method of molecular assembly that ensures maximum coverage of the short chain.  These phases are the least hydrophobic of all the MEB columns.
 
MEB2 series:  SMT MEB column with only two carbon chains.  The functional ligand is ethyl, C2 with carbon analysis results of 2% carbon load.  In these series, a very high density of the functional ligand, ethyl molecule or C2, is achieved through a novel method of molecular assembly that ensures maximum coverage.  These phases offer medium hydrophobicity when compared with all the other MEB phases.

MEB4 series:  SMT MEB column with four carbon chains.  The functional ligand is butyl, C4 with carbon analysis results of about 4% carbon load.  In these series, a very high density of the functional ligand, butyl molecule or C4, is achieved through a novel method of molecular assembly that ensures maximum coverage.  These phases offer the highest hydrophobicity when compared with all the other MEB phases.

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