Chiral compounds, or enantiomers have identical molecular structures that are related as mirror images of one another much like a left hand is related to a right hand. Rapid and accurate stereochemical resolution of enantiomeric molecules has become a challenge in various aspects of pharmaceuticals and drug discoveries. A chiral column may contain one form of an enantiomeric compound immobilized on the surface of a packing material.
The following is a list of some of the most important features for adequate separation with chiral columns:
Types of SMT Chiral available:
SMT manufactures ultra-stable chiral columns for normal and reversed-phase chromatographic separation modes. SMT uses derivatives of optically active polysaccharides that are chemically bonded on silica in the synthesis of its ChiralSep packings. Bimodal separation is made possible due to the nature of the chiral surface and the proprietary bonding technique that ensures strong chemical linkage between the chiral ligand and the silica substrate.
Are you looking for a column with custom specifications (pore size, particle size, length and/or I.D.) not available on this site? Please contact us as we can manufacture the exact column you need.
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SMT SAM ChiralSep – Specialty Chiral Column
Chiral columns for separation of enantiomers. These Chiral HPLC columns are ideal for LC-MS, and high-speed analytical, preparative and clinical methods.
SMT SAM ChiralSep Chiral – Guard Column
Chiral Guard columns are expendable small columns designed to remove anything that may interfere with the separation or shorten the lifetime of the primary column.