SMT CIB-TE columns for high performance purification of biomolecules such as proteins, enzymes, antibodies and for applications such as resolution of chiral compounds.
SMT manufactures the most reliable silica based Chemically Immobilized Biomolecules columns for both normal and reversed phase separation available in the market. SMT CIB-TE column is made through bonding of the antibiotic, Teicoplanin with 1,6-Diisocyanatohexane, using â€œTotal Coverageâ€ technology, both patented and proprietary. This covalently bonded Teicoplanin column is extremely useful for performing a wide variety of chiral separations with amino acids, carboxylic acids and neutral compounds.
Interesting characteristics such as dynamic binding capacity and specific recovery of products of interest on the columns are generally evaluated.
SMT Total Coverage technology utilizes its proprietary technique of self-assembled monolayer (SAM) of bonding to first immobilize unique mixed phases of appropriate silane ligands that are capable of effectively anchoring functional biomolecules on the silica substrates. This ensures complete elimination of non-specific binding sites on the silica surface.
The rigidity of silica particles enables the columns to be used under high performance chromatographic application and the stability of the bonded phase results in efficient purification of molecules or biomolecules of interest.
Are you looking for a column with custom specifications (pore size, particle size, length and/or I.D.) not available on this site? Please contact us as we can manufacture the exact column you need.