DEAE resins for separations of biomolecules such as proteins, nucleotides, RNAs and plasmid DNAs

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SMT-DEAE [Di-Ethyl-Amino-Ethyl] bulk provides a unique chemically attached hydrophilic, weak anion exchange type, functional surface desirable for the separation of many biomolecules such as proteins, nucleotides, oligonucleotides, polynucleotides, high molecular weight RNA’s and plasmid DNA’s. The technique of SAM is used in the bonding process to significantly increase the functional ligand density.

SMT-DEAE is silica based and the packing material is mechanically stable at high flow rates and high pressures up to 6,000 psi.

SMT-DEAE packing does not swell with organic solvents, salts, or pH gradients.

Special features of SMT-DEAE packing material include:

  • Fast reequilibration and very negligible non-specific protein interaction
  • High density tertiary amine functional groups that provide better selectivity and recovery compared to conventional DEAE
  • Highly stable silica-based anion exchange type packing material; Minimal compressibility and will not swell in organic solvents or in the presence of ion pairing reagents

We manufacture a variety of silica based bulk packing materials for analytical to large-scale purifications. SMT offers a range of bulk DEAE packings resins for those who prefer to pack their own column hardware. Samples from different lots can be purchased for method and process validation.

Silica gel and Bulk Packing materials for process scale applications are available in various particle sizes and pore sizes: 10, 20, 35, 60µm and 60, 100, 150 and 300Å are stock sizes.

Are you looking for bulk packings with custom specifications (pore size, particle size and/or quantity) not available on this site? Please contact us as we can manufacture the exact bulk media you need.

Additional information

Particle Size

35-60 µm, 10 µm, 5 µm, 3 µm, 1.7 µm

Pore Size

60Å, 100Å, 150Å, 300Å


2g, 5g, 10g, 50g, 100g, 250g, 500g, 1 KG, 2 KG, 5 KG, 10 KG, 25 KG, 50 KG, 100 KG

CAS Number