SMT manufactures bulk packings with short carbon chains for rapid analysis of basic, neutral, and mildly acidic drugs and small molecules. These columns provide excellent baseline resolution for small basic molecules including therapeutic drugs. The bonding scheme ensures proper deactivation of the substrate silanols and much better resistance to both acid and base hydrolysis. C4 (BMEB4) packing materials are silica based.
Unique features include:
- Extremely high coverage
- Highest levels of consistency and reproducibility
- High throughput – No carry over of any analytes
- Low back pressure
- Can be packed in columns (capillary, stainless steel, peek and glass)
- Analytical, solid phase extraction and process scale purification
We manufacture a variety of silica based bulk packing materials for analytical to large-scale purifications. SMT offers a range of bulk C4 resins for those who prefer to pack their own column hardware. Samples from different lots can be purchased for method and process validation.
Silica gel and Bulk Packing materials for process scale applications are available in various particle sizes and pore sizes: 10, 20, 35, 60µm and 60, 100, 150 and 300Å are stock sizes.
Are you looking for bulk packings with custom specifications (pore size, particle size and/or quantity) not available on this site? Please contact us as we can manufacture the exact bulk media you need.