SCX resins for separation of 1°, 2° and 3° amines from biological fluids

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SMT SCX Bulk Packings are silica-based Strong Cation Exchange packing materials developed for separation of cationic compounds. SMT SCX Bulk Packings consist of chemically attached hydrophilic surface derivatized to form sulfonic acid functionality. The technique of SAM is used in the bonding process to significantly increase the functional ligand density.

SMT Bulk SCX is silica based and the packing material is mechanically stable at high flow rates and high pressures up to 6,000 psi.

SMT SCX bulk packings do not swell with organic solvents, salts, or pH gradients.

Special features of SMT BSCX packing material include:

  • Superior selectivity and efficiency in the separation of proteins and biomolecules with medium to high [isoelectric point] or pH values
  • High stability under extreme operating conditions
  • High density sulfonic acid functional groups that provide improved recovery compared to conventional SCX Bulk Packings

We manufacture a variety of silica based bulk packing materials for analytical to large-scale purifications. SMT offers a range of bulk SCX packings resins for those who prefer to pack their own column hardware. Samples from different lots can be purchased for method and process validation.

Silica gel and Bulk Packing materials for process scale applications are available in various particle sizes and pore sizes: 10, 20, 35, 60µm and 60, 100, 150 and 300Å are stock sizes.

Are you looking for bulk packings with custom specifications (pore size, particle size and/or quantity) not available on this site? Please contact us as we can manufacture the exact bulk media you need.

Additional information

Particle Size

35-60 µm, 10 µm, 5 µm, 3 µm, 1.7 µm

Pore Size

60Å, 100Å, 150Å, 300Å


2g, 5g, 10g, 50g, 100g, 250g, 500g, 1 KG, 2 KG, 5 KG, 10 KG, 25 KG, 50 KG, 100 KG

CAS Number