Separation Methods Technologies, Inc. (SMT) has built a reputation as a manufacturer of the highest quality HPLC columns and chromatography media. We offer a wide selection of silica particle and pore sizes, for various chromatographic applications. The Horizontal Polymerized Bonded Phase packing material offers the benefits of maximized silica life, which reduces manufacturing down time, waste disposal, and increased overall efficiency. Â Reversed Phase ColumnsThe use of high performance liquid chromatography (HPLC) for the separation and purification of organic compounds including pharmaceuticals, natural products, food additives, organic chemicals and biologicals, has increased dramatically in the past three decades. This increase is undoubtedly associated with the enormous improvement in bonding chemistry. Various types of Reversed Phase Columns SMT has to offer:
Normal Phase ColumnsWhen chromatographic separation is done in a normal phase mode, the surface chemistry of the stationary phase has a polar characteristic. The mobile phase is generally nonpolar organic solvent (such as hexane or heptane). Normal Phase Columns SMT has to offer:
Ion Exchange ColumnsSMT has developed new series of ion-exchange packing materials with its novel SAM technology. These chromatography consumables & columns are offered for all stages of separation science from analytical scale levels to process scale purification levels. The packings are generally silica-based and consist of totally porous particles with approximately 1 Meq/g capacity. SMT packing materials allow flexibility of mobile phases. Ion Exchange Columns SMT has to offer:
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Various types of Reversed Phase Columns SMT has to offer:
Normal Phase ColumnsWhen chromatographic separation is done in a normal phase mode, the surface chemistry of the stationary phase has a polar characteristic. The mobile phase is generally nonpolar organic solvent (such as hexane or heptane). Normal Phase Columns SMT has to offer:
Ion Exchange ColumnsSMT has developed new series of ion-exchange packing materials with its novel SAM technology. These chromatography consumables & columns are offered for all stages of separation science from analytical scale levels to process scale purification levels. The packings are generally silica-based and consist of totally porous particles with approximately 1 Meq/g capacity. SMT packing materials allow flexibility of mobile phases. Ion Exchange Columns SMT has to offer:
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Specialty ColumnsWe have a special interest in surface modification and materials engineering. When separation is difficult with conventional bonded phases, SMT assists in method development and specialty chromatography column design for new applications. SMT specialty columns include special columns designed for reversed phase, normal phase, and ion exchange chromatography. These columns are specially designed for companies that are interested in having competitive advantage in separation and surface modification. Specialty Columns SMT has to offer:
Bulk Sorbents and Packing MaterialSMT Total Coverage™ chromatography packings are designed for usage from analytical to process scale purification. The primary purpose for analytical method developments in pharmaceutical and food industries is for subsequent process scale purification. The analytical steps are used to reduce the cost incurable in erroneous large-scale purification steps. SMT is a specialty column company, and as such, offers services that can greatly enhance scale-up of many analytical methods development. Bulk samples are offered for your initial evaluation. SMT offers a variety of packing materials in bulk quantities for reversed-phase, normal phase, and ion exchange chromatography. These B series bulk packing materials usually consist of silica substrates and are made with Total Coverage™ technology and guaranteed to last much longer than competitor’s silica-based packings. Polymer-based packings are made available for special applications that require use in extreme pH conditions (such as pH=14). Bulk Packings SMT has to offer:
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