Please visit us at Booth #1645
March 18 – 23, 2023
Pennsylvania Convention Center, Philadelphia, PA USA
SMT is very excited to be at Pittcon 2019!
Come visit us at Booth #3355
March 17 – 21, 2019
9:00 AM – 5:00 PM
Pennsylvania Convention Center, Philadelphia, PA USA
Visit SMT at Pittcon 2019
Please visit us at Booth #3355
March 17 – 21, 2019
9:00 AM – 5:00 PM
Pennsylvania Convention Center, Philadelphia, PA USA
Sequencing Grade Tandem Mass Spectrometry for Top-Down Proteomics Using Hybrid Electron Capture Dissociation Methods in a Benchtop Orbitrap Mass Spectrometer – SMT REFERENCED ARTICLE
Shaw JB, Malhan N, Vasil’ev YV, Lopez NI, Makarov A, Beckman JS, Voinov VG
Analytical Chemistry, 2018
Compared to traditional collision induced dissociation methods, electron capture dissociation (ECD) provides more comprehensive characterization of large peptides and proteins as well as preserves labile post-translational modifications. However, ECD experiments are generally restricted to the high magnetic fields of FTICR-MS that enable the reaction of large polycations and electrons. Here, we demonstrate the use of an electromagnetostatic ECD cell to perform ECD and hybrid ECD methods utilizing 193 nm photons (ECuvPD) or collisional activation (EChcD) in a benchtop quadrupole-Orbitrap mass spectrometer…and were packed in-house with 3 µm 300 AÌŠ C2 [BMEB2-5-300] reversed phase resin (Separation Methods Technologies, INC., Newark, DE). mAb IdeS digest (0.1 μg) was loaded onto the trap column and washed for 10 min at 5 µL/min with 1% mobile phase B…READ MORE HERE
SMT GC Columns – Coming Soon

SMT GC Columns provide extraordinary longevity, reliability and versatility
Extraction of Phytochemicals from Eucalyptus Spp. & Withania Somnifera and Their Biological Testing – SMT REFERENCED ARTICLE
Praveen Kumar Gupta, Priyanka V, Lingayya Hiremath, S Narendra Kumar, Ajeet Kumar Srivastava
American Journal of Microbiological Research, 2018
Disease incidence and prevalence is increasing in developing countries leading to high mortality and morbidity rates. Since most of the developing countries rely on traditional plant based medicine, there is huge demand for identifying the bioactive compounds from plant origin with medicinal properties owing to their safety, availability and reduced side effects. This project focuses on extraction of two different phytochemicals from Eucalyptus Spp and Withania Somnifera…HPLC analysis was carried out on a LC-20AT system (Shimadzu, Japan) using a reverse-phase C18 column [OD-5-100/25] (4.6 mm x 250 mm; Separation Methods Technologies)…READ MORE HERE
SMT SAM Reversed-Phase C18 Column

SMT SAM C18 HPLC Column and Chromatography Media
• High density octadecyl (C18) ligand, achieved through meticulous mixture of the C18 with proprietary spacer molecules to ensure maximum coverage
• Very stable at a wide pH range (1-12) and high temperatures
• Extremely sensitive and exceptional performance
• Carbon Load – OD Series: ~24%; Elite C18 Series: ~16%; ODL Series: ~12%
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SMT SAM WCX-O Mix-Mode Column

SMT SAM WCX-O Mixed-Mode silica-based columns are manufactured with weak cation exchange and hydrophobic alkyl functional groups. These advanced columns are ideal for reversed-phase, weak cation-exchange, and hydrophilic interaction liquid chromatography modes. In addition, these columns provide superior selectivity and efficiency in the separation of proteins and other biomolecules.
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SMT SAM CIB-Protein A Column

SMT CIB-Protein A Columns are designed for both high performance and low-pressure purification of antibodies Continue reading
SMT Bulk SAM SAX – Ion-Exchange Resin

SMT Bulk SAM SAX resins are silica-based strong anion exchange packings developed for the separation of compounds that form anions in aqueous solutions. The chemically attached hydrophilic surface is derivatized to form quaternary amine. It utilizes our Total Coverage bonding technology to significantly increase ligand density, high and low pH tolerance. Continue reading